The Personal Scientific Evidence System

Your source of truth
on yourself.

Concierge longevity and aesthetics, built on the first compiled-evidence layer in personal biomedicine. Every recommendation traces to a published study and a value from your biology.

Join the Waitlist How It Works
22 independently reviewed papers · 6 biomedical domains
Harvard Medical School science pipeline
By invitation & application
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Our Expertise

Two Pillars of Excellence

01

Longevity Science

Comprehensive protocols designed to optimize healthspan and extend quality of life through cutting-edge diagnostics and personalized interventions.

  • Advanced Biomarker Analysis
  • Metabolic Optimization
  • Hormone Modulation
  • Cellular Regeneration Therapies
  • Cognitive Enhancement Protocols
Learn More
02

Aesthetics

Refined aesthetic treatments that honor natural beauty while delivering transformative results through physician-led precision techniques.

  • Regenerative Skin Therapies
  • Advanced Injectable Artistry
  • Body Contouring
  • Laser & Light Treatments
  • Bespoke Skincare Protocols
Learn More
The Evidence Layer

Answers with their work shown.

Other health services give you opinions. We give you a compiled derivation — every recommendation, traced line-by-line to the published science and the values from your own biology that produced it.

Elsewhere

An opinion you have to trust

"Should I eat more legumes, given my microbiome and lipids?"
Yes — legumes are a great source of fiber and plant protein. Aim for 3–4 servings per week!
  • No source cited
  • Same answer for every patient
  • Cannot be audited or reproduced
  • Evaporates on the next model update
Live Better Science

An answer with its derivation attached

"Should I eat more legumes, given my microbiome and lipids?"
Yes — legumes score +37.31 under your plant-forward preset.
Derivation
Source
Segev et al., Nature Medicine 2026 · n = 10,068 · 4-year follow-up
Published #
WFPB strength = 22.66 · 518 microbes at q < 0.05
Your body
B. theta = 2.1% low · ApoB = 114 elevated
Compute
22.66 × 1.4 × 1.18 = 37.31
Caveats
Cohort skewed ages 45–65. Medium confidence for your ancestry subgroup.
Reproducible · Auditable · Yours
Your Data · Your Answer

Every Dossier is composed against your specific values.

Not generic health advice. Not population averages. Your Codex holds specific readings from your genome, labs, microbiome, and biomarkers — and every answer you get cites the exact values that shaped it. A few examples:

Sleep
How much sleep should I aim for, given my recovery and metabolism?
Pulled from your Codex
HRV42 mslow for age Glucose AUC132 mg/dL·hrelevated MTNR1Brs10830963 CGmelatonin variant
8.1 hours, with a sleep window from 10:30 PM → 6:45 AM. An earlier bedtime is recommended because your HRV of 42 ms is in the bottom quartile for your age and your glucose AUC of 132 signals impaired glycemic recovery. Your MTNR1B CG variant shifts melatonin onset ~27 minutes later unless evening blue-light exposure is reduced after 8 PM.
Walker lab sleep meta-analyses · Lane et al. MTNR1B variants 2024 · your Jan 2026 Oura + Apr Function panel
Supplements
Should I take creatine?
Pulled from your Codex
Muscle mass38.2 kgbottom quartile for your BMI TCF7L2rs7903146 CTinsulin-response variant eGFR94 mL/min/1.73m²normal
Yes — 3–5 g/day, monohydrate, any time of day. Specifically because your muscle mass (38.2 kg) is bottom-quartile for your BMI, and because your TCF7L2 rs7903146 CT genotype benefits from creatine's glucose-buffering effect beyond the musculoskeletal outcome. Your eGFR of 94 clears creatine safely. Does not affect your lipid panel.
Kreider et al 2017 meta-analysis · TCF7L2 insulin-resistance literature · your Mar DEXA + May metabolic panel
Cardio Risk
What's my 10-year cardiovascular risk?
Pulled from your Codex
ApoB114 mg/dLelevated Lp(a)48 nmol/Labove 30 threshold Polygenic CVD score82nd %ileabove-average risk SBP avg128 mmHgstage 1
4.8% 10-year MACE risk. Elevated versus your age/sex peers. Primary drivers: your Lp(a) of 48 (genetic, roughly 2× median) and your 82nd-percentile polygenic score. The modifiable lever is your ApoB of 114 — target < 80 over 6 months. Your SBP of 128 is below the CVD-risk threshold at this age; monitor but no intervention required.
MESA 10-yr MACE model · UK Biobank PRS · Lp(a) 2024 ACC consensus · your Apr lipid + Feb genome
Aesthetics
Which active ingredients will improve my skin barrier?
Pulled from your Codex
Malassezia12%vs 3% median C. acnes38%elevated FLGrs61816761 CTfilaggrin variant
Niacinamide 4% + azelaic acid 10%. Avoid heavy occlusives. Azelaic specifically because your Malassezia load of 12% is 4× median — azelaic is among the few antifungally active topicals proven in Malassezia folliculitis. Niacinamide addresses your FLG CT variant, which reduces baseline filaggrin production. Your C. acnes load of 38% means occlusive moisturizers will worsen, not improve, your barrier.
Del Rosso 2023 Malassezia review · FLG variant 2024 dermatology literature · your Mar skin-microbiome + Feb genome

Every answer you get is traceable. Every member-data chip above is pulled from a real reading in your Codex. Every published reference can be opened, read, and checked. Every number can be re-computed. Your Dossier library grows with every question — yours forever, versioned, durable across every future model and every future doctor.

Our Philosophy

Medicine should show its work.

"Your body deserves answers that are sourced, personalized, and durable. Not opinions. Not trends. Not recommendations that change when the model changes."

Live Better Science operates at the intersection of peer-reviewed biomedicine and personalized care. Every protocol is compiled from specific published studies against the specific values from your diagnostics — with the full derivation attached. The result is a personal evidence archive that belongs to you, grows with every consult, and persists across every future change in science or medicine.

At the Frontier

The substrate arrived this quarter.

Frontier biology models from DeepMind, OpenAI, Anthropic, and Arc Institute all shipped in the last six months. We compose them into one evidence-grade engine behind every protocol — so you get the best of science as soon as it exists, not years later.

Frontier biology models

Published this year in Nature and Science. We use the newest foundation models for genomic variant effect, protein structure, and cellular analysis the moment they are released.

  • Million-base genomic context for variant interpretation
  • Structure prediction for protein & drug-binding questions
  • Single-cell and tissue analysis for deep diagnostics

Reasoning over the literature

Our compiler reads full peer-reviewed papers — not abstracts, not summaries — and composes answers grounded in the specific published numbers your protocol needs.

  • Full-paper reasoning across PubMed, bioRxiv, supplementary tables
  • Multi-paper synthesis with citation-grade provenance
  • Updated continuously as new research is published

Your data, sovereign

Genome, labs, microbiome, epigenetic age, hormones, continuous monitors — structured and owned by you. The archive grows with every consult and outlives every model update.

  • Structured personal evidence archive
  • Versioned, auditable, portable across clinicians
  • Consent-forward — you control how it's used
"The frontier of longevity science is no longer theoretical. It is measurable, programmable, and deeply personal — and, for the first time, the tools to compile it against your body have arrived."
01
Consultation
A confidential conversation to understand your goals, history, and vision for optimal health.
02
Diagnostics
Comprehensive biomarker analysis, genomic profiling, and baseline assessment.
03
Protocol Design
A bespoke intervention plan built from your data, calibrated to your biology.
04
Optimization
Ongoing tracking, refinement, and iteration as your biomarkers evolve.
Waitlist · Pre-Launch

Join the Waitlist

Membership will open by invitation and application. Leave your email and we'll reach out when the first cohort opens — with first access and founding-member pricing.

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